INHIBITION OF FOXO1/3 PROMOTES VASCULAR CALCIFICATION

OBJECTIVE: Vascular calcification is a characteristic feature of atherosclerosis, diabetes and end-stage renal disease. We have demonstrated that activation of AKT upregulates Runx2, a key osteogenic transcription factor that is crucial for calcification of vascular smooth muscle cells (VSMC). Using...

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發表在:Arterioscler Thromb Vasc Biol
Main Authors: Deng, Liang, Huang, Lu, Sun, Yong, Heath, Jack M, Wu, Hui, Chen, Yabing
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270841/
https://ncbi.nlm.nih.gov/pubmed/25378413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304786
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