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INHIBITION OF FOXO1/3 PROMOTES VASCULAR CALCIFICATION
OBJECTIVE: Vascular calcification is a characteristic feature of atherosclerosis, diabetes and end-stage renal disease. We have demonstrated that activation of AKT upregulates Runx2, a key osteogenic transcription factor that is crucial for calcification of vascular smooth muscle cells (VSMC). Using...
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| Izdano u: | Arterioscler Thromb Vasc Biol |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270841/ https://ncbi.nlm.nih.gov/pubmed/25378413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304786 |
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