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HSV-2-Driven Increase in the Expression of α(4)β(7) Correlates with Increased Susceptibility to Vaginal SHIV(SF162P3) Infection

The availability of highly susceptible HIV target cells that can rapidly reach the mucosal lymphoid tissues may increase the chances of an otherwise rare transmission event to occur. Expression of α(4)β(7) is required for trafficking of immune cells to gut inductive sites where HIV can expand and it...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Goode, Diana, Truong, Rosaline, Villegas, Guillermo, Calenda, Giulia, Guerra-Perez, Natalia, Piatak, Michael, Lifson, Jeffrey D., Blanchard, James, Gettie, Agegnehu, Robbiani, Melissa, Martinelli, Elena
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270786/
https://ncbi.nlm.nih.gov/pubmed/25521298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004567
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