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Reexpression of the Rat Hypoxanthine Phosphoribosyltransferase Gene in Rat-Human Hybrids

Fusion of hypoxanthine phosphoribosyltransferase (HPRT)(-) rat hepatoma cells with HPRT(+) human fibroblasts yielded hybrid clones that grew in HAT selective medium and contained all the rat chromosomes and one to nine human chromosomes. Among the retained chromosomes was the human X chromosome. In...

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Autori principali: Croce, Carlo M., Bakay, Bohdan, Nyhan, William L., Koprowski, Hilary
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1973
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC427062/
https://ncbi.nlm.nih.gov/pubmed/4354857
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