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Effect of cyclin-dependent kinase 7 silencing on cisplatin sensitivity in endometrial carcinoma cells

The aim of the present study was to determine the effect of cyclin-dependent kinase 7 (CDK7) silencing on the sensitivity of the HEC-1-A endometrial carcinoma cell line to cisplatin [cis-dichlorodiammineplatinum (II), or DDP]. Four CDK7 siRNA fragments were designed and synthesized based on the gene...

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Détails bibliographiques
Publié dans:Mol Med Rep
Auteurs principaux: LIU, WEN-XIN, LIU, XIANG-YU, YU, HU, CHEN, YING, HAO, QUAN
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270335/
https://ncbi.nlm.nih.gov/pubmed/25411854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2014.2980
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