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Leptin receptor deficiency confers resistance to behavioral effects of fluoxetine and desipramine via separable substrates

Depression is a complex, heterogeneous mental disorder. Currently available antidepressants are only effective in about one-third to one-half of all patients. The mechanisms underlying antidepressant response and treatment resistance are poorly understood. Recent clinical evidence implicates the inv...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Guo, M, Lu, X-Y
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270309/
https://ncbi.nlm.nih.gov/pubmed/25463972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2014.126
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