Localization of Antibody-Combining Sites within the Variable Portions of Heavy and Light Chains
The Fab′-fragment of a mouse IgA-myeloma (protein-315) was split by pepsin to yield a smaller fragment that retained the anti-2,4-dinitrophenyl activity of the intact protein. This fragment, which we call Fv, has a molecular weight of about 30,000 (half that of Fab′), and is composed of two polypept...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1972
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427010/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4560694/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.9.2659 |
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