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Localization of Antibody-Combining Sites within the Variable Portions of Heavy and Light Chains
The Fab′-fragment of a mouse IgA-myeloma (protein-315) was split by pepsin to yield a smaller fragment that retained the anti-2,4-dinitrophenyl activity of the intact protein. This fragment, which we call Fv, has a molecular weight of about 30,000 (half that of Fab′), and is composed of two polypept...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1972
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC427010/ https://ncbi.nlm.nih.gov/pubmed/4560694 |
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