Proteomics informed by transcriptomics reveals Hendra virus sensitizes bat cells to TRAIL-mediated apoptosis

BACKGROUND: Bats are a major reservoir of emerging infectious viruses. Many of these viruses are highly pathogenic to humans however bats remain asymptomatic. The mechanism by which bats control viral replication is unknown. Here we utilize an integrated approach of proteomics informed by transcript...

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Vydáno v:Genome Biol
Hlavní autoři: Wynne, James W, Shiell, Brian J, Marsh, Glenn A, Boyd, Victoria, Harper, Jennifer A, Heesom, Kate, Monaghan, Paul, Zhou, Peng, Payne, Jean, Klein, Reuben, Todd, Shawn, Mok, Lawrence, Green, Diane, Bingham, John, Tachedjian, Mary, Baker, Michelle L, Matthews, David, Wang, Lin-Fa
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269970/
https://ncbi.nlm.nih.gov/pubmed/25398248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0532-x
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