Proteomics informed by transcriptomics reveals Hendra virus sensitizes bat cells to TRAIL-mediated apoptosis

BACKGROUND: Bats are a major reservoir of emerging infectious viruses. Many of these viruses are highly pathogenic to humans however bats remain asymptomatic. The mechanism by which bats control viral replication is unknown. Here we utilize an integrated approach of proteomics informed by transcript...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Wynne, James W, Shiell, Brian J, Marsh, Glenn A, Boyd, Victoria, Harper, Jennifer A, Heesom, Kate, Monaghan, Paul, Zhou, Peng, Payne, Jean, Klein, Reuben, Todd, Shawn, Mok, Lawrence, Green, Diane, Bingham, John, Tachedjian, Mary, Baker, Michelle L, Matthews, David, Wang, Lin-Fa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269970/
https://ncbi.nlm.nih.gov/pubmed/25398248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0532-x
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