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Apoptosis imaging for monitoring DR5 antibody accumulation and pharmacodynamics in brain tumors non-invasively

High grade gliomas often possess an impaired blood-brain barrier (BBB) which allows delivery of large molecules to brain tumors. However, achieving optimal drug concentrations in brain tumors remains a significant hurdle for treating patients successfully. Thus, detailed investigations of drug activ...

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Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Weber, Thomas G., Osl, Franz, Renner, Anja, Pöschinger, Thomas, Galbán, Stefanie, Rehemtulla, Alnawaz, Scheuer, Werner
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269941/
https://ncbi.nlm.nih.gov/pubmed/24509903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3001
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