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Noninvasive Monitoring of Pharmacodynamics and Kinetics of a Death Receptor 5 Antibody and Its Enhanced Apoptosis Induction in Sequential Application with Doxorubicin
Induction of apoptosis plays a crucial role in the response of tumors to treatment. Thus, we investigated the pharmacodynamics and tumor saturation kinetics of a death receptor 5 antibody (anti-DR5) when combined with chemotherapeutics. For our investigations, we applied an imaging method that allow...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Neoplasia Press Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3730039/ https://ncbi.nlm.nih.gov/pubmed/23908588 |
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