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Rational design of nonnatural peptides as high-affinity ligands for the HLA-B*2705 human leukocyte antigen.

From the three-dimensional structure of the class I major histocompatibility complex (MHC) HLA-B*2705 protein, several nonnatural peptides were designed either to optimize the interactions of one peptide amino acid (position 3) with its HLA binding pocket (pocket D) or to simplify the T-cell recepto...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Rognan, D, Scapozza, L, Folkers, G, Daser, A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1995
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42698/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846047/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.753
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