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Rational design of nonnatural peptides as high-affinity ligands for the HLA-B*2705 human leukocyte antigen.

From the three-dimensional structure of the class I major histocompatibility complex (MHC) HLA-B*2705 protein, several nonnatural peptides were designed either to optimize the interactions of one peptide amino acid (position 3) with its HLA binding pocket (pocket D) or to simplify the T-cell recepto...

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Detalhes bibliográficos
Main Authors: Rognan, D, Scapozza, L, Folkers, G, Daser, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC42698/
https://ncbi.nlm.nih.gov/pubmed/7846047
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