Rational design of nonnatural peptides as high-affinity ligands for the HLA-B*2705 human leukocyte antigen.
From the three-dimensional structure of the class I major histocompatibility complex (MHC) HLA-B*2705 protein, several nonnatural peptides were designed either to optimize the interactions of one peptide amino acid (position 3) with its HLA binding pocket (pocket D) or to simplify the T-cell recepto...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42698/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846047/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.753 |
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