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The Role of Histone Tails in the Nucleosome: A Computational Study

Histone tails play an important role in gene transcription and expression. We present here a systematic computational study of the role of histone tails in the nucleosome, using replica exchange molecular dynamics simulations with an implicit solvent model and different well-established force fields...

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Publicat a:Biophys J
Autors principals: Erler, Jochen, Zhang, Ruihan, Petridis, Loukas, Cheng, Xiaolin, Smith, Jeremy C., Langowski, Jörg
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269774/
https://ncbi.nlm.nih.gov/pubmed/25517156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.065
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