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Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: a (13)C-NMR study

Alzheimer's disease (AD) is characterized by age-dependent biochemical, metabolic, and physiologic changes. These age-dependent changes ultimately converge to impair cognitive functions. This study was carried out to examine the metabolic changes by probing glucose and tricarboxylic acid cycle...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Sancheti, Harsh, Patil, Ishan, Kanamori, Keiko, Díaz Brinton, Roberta, Zhang, Wei, Lin, Ai-Ling, Cadenas, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269751/
https://ncbi.nlm.nih.gov/pubmed/25099753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.137
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