Accurate determination of blood–brain barrier permeability using dynamic contrast-enhanced T1-weighted MRI: a simulation and in vivo study on healthy subjects and multiple sclerosis patients

Dynamic contrast-enhanced magnetic resonance imaging (DCE–MRI) is increasingly used to estimate permeability in situations with subtle blood–brain barrier (BBB) leakage. However, the method's ability to differentiate such low values from zero is unknown, and no consensus exists on optimal selec...

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Pubblicato in:J Cereb Blood Flow Metab
Autori principali: Cramer, Stig P, Larsson, Henrik B W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269724/
https://ncbi.nlm.nih.gov/pubmed/25074746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.126
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