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Accurate determination of blood–brain barrier permeability using dynamic contrast-enhanced T1-weighted MRI: a simulation and in vivo study on healthy subjects and multiple sclerosis patients

Dynamic contrast-enhanced magnetic resonance imaging (DCE–MRI) is increasingly used to estimate permeability in situations with subtle blood–brain barrier (BBB) leakage. However, the method's ability to differentiate such low values from zero is unknown, and no consensus exists on optimal selec...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Cramer, Stig P, Larsson, Henrik B W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269724/
https://ncbi.nlm.nih.gov/pubmed/25074746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.126
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