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Constitutive PKA activity is essential for maintaining the excitability and contractility in guinea pig urinary bladder smooth muscle: role of the BK channel

The elevation of protein kinase A (PKA) activity activates the large-conductance voltage- and Ca(2+)-activated K(+) (BK) channels in urinary bladder smooth muscle (UBSM) cells and consequently attenuates spontaneous phasic contractions of UBSM. However, the role of constitutive PKA activity in UBSM...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Cell Physiol
Main Authors: Xin, Wenkuan, Li, Ning, Cheng, Qiuping, Fernandes, Vitor S., Petkov, Georgi V.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269660/
https://ncbi.nlm.nih.gov/pubmed/25318105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00167.2014
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