Electroporation mediated gene delivery of Na(+),K(+)-ATPase and ENaC subunits to the lung attenuates acute respiratory distress syndrome in a two-hit porcine model

INTRODUCTION: Acute Respiratory Distress Syndrome (ARDS) is a common cause of organ failure with an associated mortality rate of 40%. The initiating event is disruption of alveolar-capillary interface causing leakage of edema into alveoli. Hypothesis: Electroporation mediated gene delivery of epithe...

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Publicado no:Shock
Main Authors: Emr, Bryanna M, Roy, Shreyas, Kollisch-Singule, Michaela, Gatto, Louis A., Barravecchia, Michael, Lin, Xin, Young, Jennifer L., Wang, Guirong, Liu, Jiao, Satalin, Joshua, Snyder, Kathleen, Nieman, Gary F., Dean, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269562/
https://ncbi.nlm.nih.gov/pubmed/25004064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000228
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