Design, Synthesis, Antiviral Activity, and Pre-formulation Development of Poly-L-Arginine-Fatty acyl Derivatives of Nucleoside Reverse Transcriptase Inhibitors

The objective of this work was to design conjugates of anti-HIV nucleosides conjugated with fatty acids and cell penetrating poly-L-arginine (polyArg) peptides. Three conjugates of polyArg cell-penetrating peptides with fatty acyl derivatives of alovudine (FLT), lamivudine (3TC), and emtricitabine (...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleosides Nucleotides Nucleic Acids
Main Authors: Pemmaraju, Bhanu P., Malekar, Swapnil, Agarwal, Hitesh K., Tiwari, Rakesh K., Oh, Donghoon, Doncel, Gustavo F., Worthen, David R., Parang, Keykavous
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269296/
https://ncbi.nlm.nih.gov/pubmed/25513860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770.2014.945649
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados