X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine.

We have determined the x-ray structure of a DNA fragment containing 7,8-dihydro-8-oxoguanine (G(O)). The structure of the duplex form of d(CCAGOCGCTGG) has been determined to 1.6-A resolution. The results demonstrate that GO forms Watson-Crick base pairs with the opposite C and that G(O) is in the a...

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Main Authors: Lipscomb, L A, Peek, M E, Morningstar, M L, Verghis, S M, Miller, E M, Rich, A, Essigmann, J M, Williams, L D
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC42691/
https://ncbi.nlm.nih.gov/pubmed/7846041
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