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X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine.

We have determined the x-ray structure of a DNA fragment containing 7,8-dihydro-8-oxoguanine (G(O)). The structure of the duplex form of d(CCAGOCGCTGG) has been determined to 1.6-A resolution. The results demonstrate that GO forms Watson-Crick base pairs with the opposite C and that G(O) is in the a...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lipscomb, L A, Peek, M E, Morningstar, M L, Verghis, S M, Miller, E M, Rich, A, Essigmann, J M, Williams, L D
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846041/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.719
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