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Pathway activity inference for multiclass disease classification through a mathematical programming optimisation framework

BACKGROUND: Applying machine learning methods on microarray gene expression profiles for disease classification problems is a popular method to derive biomarkers, i.e. sets of genes that can predict disease state or outcome. Traditional approaches where expression of genes were treated independently...

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Библиографические подробности
Опубликовано в: :BMC Bioinformatics
Главные авторы: Yang, Lingjian, Ainali, Chrysanthi, Tsoka, Sophia, Papageorgiou, Lazaros G
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269079/
https://ncbi.nlm.nih.gov/pubmed/25475756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-014-0390-2
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