Pathway activity inference for multiclass disease classification through a mathematical programming optimisation framework

BACKGROUND: Applying machine learning methods on microarray gene expression profiles for disease classification problems is a popular method to derive biomarkers, i.e. sets of genes that can predict disease state or outcome. Traditional approaches where expression of genes were treated independently...

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Publicat a:BMC Bioinformatics
Autors principals: Yang, Lingjian, Ainali, Chrysanthi, Tsoka, Sophia, Papageorgiou, Lazaros G
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269079/
https://ncbi.nlm.nih.gov/pubmed/25475756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-014-0390-2
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