Retinal antigen-specific regulatory T cells protect against spontaneous and induced autoimmunity and require local dendritic cells

BACKGROUND: We previously reported that the peripheral regulatory T cells (pTregs) generated ‘on-demand’ in the retina were crucial to retinal immune privilege, and in vitro analysis of retinal dendritic cells (DC) showed they possessed antigen presenting cell (APC) activity that promoted developmen...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: McPherson, Scott W, Heuss, Neal D, Pierson, Mark J, Gregerson, Dale S
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268905/
https://ncbi.nlm.nih.gov/pubmed/25498509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0205-4
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