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Local “On-Demand” Generation and Function of Antigen Specific FoxP3(+) Regulatory T cells()

Extrathymically derived regulatory T cells (iTregs) protect against autoimmunity to tissue-specific antigens (Ag). However, whether Ag-specific iTreg generation and function is limited to secondary lymphoid tissue or whether it can occur within the tissue-specific, local environment of the cognate A...

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Detalhes bibliográficos
Main Authors: McPherson, Scott W., Heuss, Neal D., Gregerson, Dale S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646944/
https://ncbi.nlm.nih.gov/pubmed/23585681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202625
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