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Short-term diesel exhaust inhalation in a controlled human crossover study is associated with changes in DNA methylation of circulating mononuclear cells in asthmatics

BACKGROUND: Changes in DNA methylation have been associated with traffic-related air pollution in observational studies, but the specific mechanisms and temporal dynamics therein have not been explored in a controlled study of asthmatics. In this study, we investigate short-term effects of diesel ex...

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Publicat a:Part Fibre Toxicol
Autors principals: Jiang, Ruiwei, Jones, Meaghan J, Sava, Francesco, Kobor, Michael S, Carlsten, Christopher
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268899/
https://ncbi.nlm.nih.gov/pubmed/25487561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-014-0071-3
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