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MicroRNA Expression in Response to Controlled Exposure to Diesel Exhaust: Attenuation by the Antioxidant N-Acetylcysteine in a Randomized Crossover Study

Background: Adverse health effects associated with diesel exhaust (DE) are thought to be mediated in part by oxidative stress, but the detailed mechanisms are largely unknown. MicroRNAs (miRNAs) regulate gene expression post-transcriptionally and may respond to exposures such as DE. Objectives: We p...

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Главные авторы: Yamamoto, Masatsugu, Singh, Amrit, Sava, Francesco, Pui, Mandy, Tebbutt, Scott J., Carlsten, Christopher
Формат: Artigo
Язык:Inglês
Опубликовано: National Institute of Environmental Health Sciences 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672916/
https://ncbi.nlm.nih.gov/pubmed/23584289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1205963
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