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Cell type-specific delivery of short interfering RNAs by dye-functionalised theranostic nanoparticles

Efficient delivery of short interfering RNAs reflects a prerequisite for the development of RNA interference therapeutics. Here, we describe highly specific nanoparticles, based on near infrared fluorescent polymethine dye-derived targeting moieties coupled to biodegradable polymers. The fluorescent...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Press, Adrian T., Traeger, Anja, Pietsch, Christian, Mosig, Alexander, Wagner, Michael, Clemens, Mark G., Jbeily, Nayla, Koch, Nicole, Gottschaldt, Michael, Bézière, Nicolas, Ermolayev, Volodymyr, Ntziachristos, Vasilis, Popp, Jürgen, Kessels, Michael M., Qualmann, Britta, Schubert, Ulrich S., Bauer, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268698/
https://ncbi.nlm.nih.gov/pubmed/25470305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6565
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