Cell type-specific delivery of short interfering RNAs by dye-functionalised theranostic nanoparticles

Efficient delivery of short interfering RNAs reflects a prerequisite for the development of RNA interference therapeutics. Here, we describe highly specific nanoparticles, based on near infrared fluorescent polymethine dye-derived targeting moieties coupled to biodegradable polymers. The fluorescent...

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Publicat a:Nat Commun
Autors principals: Press, Adrian T., Traeger, Anja, Pietsch, Christian, Mosig, Alexander, Wagner, Michael, Clemens, Mark G., Jbeily, Nayla, Koch, Nicole, Gottschaldt, Michael, Bézière, Nicolas, Ermolayev, Volodymyr, Ntziachristos, Vasilis, Popp, Jürgen, Kessels, Michael M., Qualmann, Britta, Schubert, Ulrich S., Bauer, Michael
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268698/
https://ncbi.nlm.nih.gov/pubmed/25470305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6565
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