T Cell Receptor-Engineered T Cells to Treat Solid Tumors: T Cell Processing Toward Optimal T Cell Fitness

Therapy with autologous T cells that have been gene-engineered to express chimeric antigen receptors (CAR) or T cell receptors (TCR) provides a feasible and broadly applicable treatment for cancer patients. In a clinical study in advanced renal cell carcinoma (RCC) patients with CAR T cells specific...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther Methods
Main Authors: Lamers, Cor H.J., van Steenbergen-Langeveld, Sabine, van Brakel, Mandy, Groot-van Ruijven, Corrien M., van Elzakker, Pascal M.M.L., van Krimpen, Brigitte, Sleijfer, Stefan, Debets, Reno
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268575/
https://ncbi.nlm.nih.gov/pubmed/25423330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2014.051
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