Treatment intensification with maraviroc (CCR5 antagonist) leads to declines in CD16-expressing monocytes in cART-suppressed chronic HIV-infected subjects and is associated with improvements in neurocognitive test performance: implications for HIV-associated neurocognitive disease (HAND)

HIV-associated neurocognitive disorders (HAND) continues to be prevalent (30–50 %) despite plasma HIVRNA suppression with combination antiretroviral therapy (cART). There is no proven therapy for individuals on suppressive cARTwith HAND. We have shown that the degree of HIV reservoir burden (HIV DNA...

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Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Ndhlovu, Lishomwa C., Umaki, Tracie, Chew, Glen M., Chow, Dominic C., Agsalda, Melissa, Kallianpur, Kalpana J., Paul, Robert, Zhang, Guangxiang, Ho, Erika, Hanks, Nancy, Nakamoto, Beau, Shiramizu, Bruce T., Shikuma, Cecilia M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268390/
https://ncbi.nlm.nih.gov/pubmed/25227930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-014-0279-x
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