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Effect of Environmental pH on the Efficiency of Cellular Hybridization

The hybridization of a human and mouse cell was strikingly pH-dependent, with a well defined optimum at (about) pH 7.6-8.0. The yield of hybrid cell colonies (1 per 500-2000 heterokaryocytes) was several hundred times greater than that obtained at pH 6.8-7.2. Although there was a significant effect...

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Detalles Bibliográficos
Main Authors: Croce, Carlo M., Koprowski, Hilary, Eagle, Harry
Formato: Artigo
Idioma:Inglês
Publicado: 1972
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC426839/
https://ncbi.nlm.nih.gov/pubmed/4340167
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