Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression

Misexpression of developmental transcription factors occurs often in human cancers, where embryonic programs may be reinstated in a context that promotes or sustains malignant development. In this study, we report the involvement of the kidney development transcription factor Six2 in the metastatic...

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Vydáno v:Cancer Res
Hlavní autoři: Wang, Chu-An, Drasin, David, Pham, Catherine, Jedlicka, Paul, Zaberezhnyy, Vadym, Guney, Michelle, Li, Howard, Nemenoff, Raphael, Costello, James C., Tan, Aik-Choon, Ford, Heide L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268359/
https://ncbi.nlm.nih.gov/pubmed/25348955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0666
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