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Regulation of Rotavirus Polymerase Activity by Inner Capsid Proteins

Rotavirus, a cause of pediatric gastroenteritis, has a genome consisting of 11 segments of double-stranded (ds)RNA surrounded by a triple-layered protein capsid. The rotavirus RNA-dependent RNA polymerase, VP1, synthesizes both dsRNA and plus-strand RNA (+RNA) within subviral particles. Structural a...

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Foilsithe in:Curr Opin Virol
Main Authors: Gridley, Chelsea L., Patton, John T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268341/
https://ncbi.nlm.nih.gov/pubmed/25243800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2014.08.008
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