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Regulation of Rotavirus Polymerase Activity by Inner Capsid Proteins
Rotavirus, a cause of pediatric gastroenteritis, has a genome consisting of 11 segments of double-stranded (ds)RNA surrounded by a triple-layered protein capsid. The rotavirus RNA-dependent RNA polymerase, VP1, synthesizes both dsRNA and plus-strand RNA (+RNA) within subviral particles. Structural a...
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Publicado no: | Curr Opin Virol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268341/ https://ncbi.nlm.nih.gov/pubmed/25243800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2014.08.008 |
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