Synthesis and characterization of different immunogenic viral nanoconstructs from rotavirus VP6 inner capsid protein

In order to deliver low-cost viral capsomeres from a large amount of soluble viral VP6 protein from human rotavirus, we developed and optimized a biotechnological platform in Escherichia coli. Specifically, three different expression protocols were compared, differing in their genetic constructs, ie...

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Bibliographic Details
Main Authors: Bugli, Francesca, Caprettini, Valeria, Cacaci, Margherita, Martini, Cecilia, Paroni Sterbini, Francesco, Torelli, Riccardo, Della Longa, Stefano, Papi, Massimiliano, Palmieri, Valentina, Giardina, Bruno, Posteraro, Brunella, Sanguinetti, Maurizio, Arcovito, Alessandro
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2014
Subjects:
Methodology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047981/
https://ncbi.nlm.nih.gov/pubmed/24936129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S60014
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