An evolutionary arms race between KRAB zinc finger genes 91/93 and SVA/L1 retrotransposons

Throughout evolution, primate genomes have been modified by waves of retrotransposon insertions(1,2,3). For each wave, the host eventually finds a way to repress retrotransposon transcription and prevent further insertions. In mouse embryonic stem cells (mESCs), transcriptional silencing of retrotra...

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Gepubliceerd in:Nature
Hoofdauteurs: Jacobs, Frank MJ, Greenberg, David, Nguyen, Ngan, Haeussler, Maximilian, Ewing, Adam D, Katzman, Sol, Paten, Benedict, Salama, Sofie R, Haussler, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268317/
https://ncbi.nlm.nih.gov/pubmed/25274305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13760
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