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A tissue-specific promoter that can drive a foreign gene to express in the suprabasal urothelial cells of transgenic mice.

Uroplakins are a group of integral membrane proteins that are synthesized as the major differentiation products of urothelium. The luminal portions of these proteins form 12-nm protein particles arranged in a two-dimensional crystalline array. The expression of uroplakin genes is bladder specific an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Lin, J H, Zhao, H, Sun, T T
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42683/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846036/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.679
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