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Intranasal delivery of liposomal indole-3-carbinol improves its pulmonary bioavailability
Indole-3-carbinol (I3C), a constituent of commonly consumed Brassica vegetables, has been shown to have anticancer effects in a variety of preclinical models of lung cancer. However, it has shown only limited efficacy in clinical trials, likely due to its poor oral bioavailability. Intranasal admini...
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| Veröffentlicht in: | Int J Pharm |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268270/ https://ncbi.nlm.nih.gov/pubmed/25311179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2014.10.018 |
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