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System A Amino Acid Transport-Targeted Brain and Systemic Tumor PET Imaging Agents 2-Amino-3-[(18)F]Fluoro-2-Methylpropanoic Acid and 3-[(18)F]Fluoro-2-Methyl-2-(Methylamino)propanoic Acid

INTRODUCTION: Amino acid based radiotracers target tumor cells through increased uptake by membrane-associated amino acid transport (AAT) systems. In the present study, four structurally related non-natural (18)F-labeled amino acids, (R)- and (S)-[(18)F]FAMP 1 and (R)- and (S)-[(18)F]MeFAMP 2 have b...

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Detalhes bibliográficos
Publicado no:Nucl Med Biol
Main Authors: Yu, Weiping, McConathy, Jonathan, Olson, Jeffrey J., Goodman, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268243/
https://ncbi.nlm.nih.gov/pubmed/25263130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2014.07.002
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