Neurofibromin Deficiency-Associated Transcriptional Dysregulation Suggests a Novel Therapy for Tibial Pseudoarthrosis in NF1

Neurofibromatosis type 1 (NF1) is an autosomal dominant disease caused by mutations in NF1. Among the earliest manifestations is tibial pseudoarthrosis and persistent nonunion after fracture. To further understand the pathogenesis of pseudoarthrosis and the underlying bone remodeling defect, pseudoa...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Paria, Nandina, Cho, Tae-Joon, Choi, In Ho, Kamiya, Nobuhiro, Kayembe, Kay, Mao, Rong, Margraf, Rebecca L., Obermosser, Gerlinde, Oxendine, Ila, Sant, David W., Song, Mi Hyun, Stevenson, David A., Viskochil, David H., Wise, Carol A., Kim, Harry K.W., Rios, Jonathan J
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268180/
https://ncbi.nlm.nih.gov/pubmed/24932921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2298
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