Telomere elongation and naïve pluripotent stem cells achieved from telomerase haplo-insufficient cells by somatic cell nuclear transfer

Haplo-insufficiency of telomerase genes in humans leads to telomere syndromes such as dyskeratosis congenital and idiopathic pulmonary fibrosis. Generation of pluripotent stem cells from telomerase haplo-insufficient donor cells would provide unique opportunities towards the realization of patient-s...

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Vydáno v:Cell Rep
Hlavní autoři: Sung, Li-Ying, Chang, Wei-Fang, Zhang, Qian, Liu, Chia-Chia, Liou, Jun-Yang, Chang, Chia-Chun, Ou-Yang, Huan, Guo, Renpeng, Fu, Haifeng, Cheng, Winston T.K., Ding, Shih-Torng, Chen, Chuan-Mu, Okuka, Maja, Keefe, David L, Chen, Y. Eugene, Liu, Lin, Xu, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268138/
https://ncbi.nlm.nih.gov/pubmed/25464850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.052
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