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Polypeptide Chain Initiation in Eukaryotes: Functional Identity of Supernatant Factor from Various Sources

Eukaryotic cells contain polypeptide chain initiation factors that, like the prokaryotic initiation factor IF-2, promote the AUG-dependent binding of fMet-tRNA(f) to the small ribosomal subunit. The bound amino-acyl-tRNA is directly convertible to fMet-puromycin upon addition of 60S subunit. The rea...

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Main Authors: Zasloff, Michael, Ochoa, Severo
格式: Artigo
語言:Inglês
出版: 1972
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC426804/
https://ncbi.nlm.nih.gov/pubmed/4558658
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