Polypeptide Chain Initiation in Eukaryotes: Functional Identity of Supernatant Factor from Various Sources

Eukaryotic cells contain polypeptide chain initiation factors that, like the prokaryotic initiation factor IF-2, promote the AUG-dependent binding of fMet-tRNA(f) to the small ribosomal subunit. The bound amino-acyl-tRNA is directly convertible to fMet-puromycin upon addition of 60S subunit. The rea...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Zasloff, Michael, Ochoa, Severo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1972
Schlagworte:	Biological Sciences: Biochemistry
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4558658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.7.1796
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