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A distal locus element mediates IFN-γ priming of LPS-stimulated TNF gene expression
IFN-γ priming sensitizes monocytes/macrophages to lipopolysaccharide (LPS) stimulation, resulting in augmented expression of a set of genes including TNF. Here, we demonstrate that IFN-γ priming of LPS-stimulated TNF transcription requires a distal TNF/LT locus element 8 kb upstream of the TNF trans...
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| Udgivet i: | Cell Rep |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268019/ https://ncbi.nlm.nih.gov/pubmed/25482561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.11.011 |
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