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The Cdk5 Activator P39 Specifically Links Muskelin to Myosin II and Regulates Stress Fiber Formation and Actin Organization in Lens

Cyclin dependent kinase 5 (Cdk5), a proline-directed serine/threonine kinase, requires p39 for its enzymatic activity, and is implicated in cytoskeletal organization and contraction in numerous cell types. The C-terminus of p39 binds muskelin, a multi-domain scaffolding protein known to affect cytos...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Tripathi, Brajendra K., Lowy, Douglas R., Zelenka, Peggy S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268005/
https://ncbi.nlm.nih.gov/pubmed/25128817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.08.003
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