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Functional Nonequivalence of α and β Hemes in Human Adult Hemoglobin

Nuclear magnetic resonance studies of the contact-shifted spectra of heme protons in deoxyhemoglobin A from human adults show conclusively that oxygen binds to the α hemes in preference to the β hemes. The preferential binding is produced in 10% hemoglobin solution at neutral pH by either a 15-fold...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lindstrom, Ted R., Ho, Chien
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4505648/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.7.1707
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