Excretion of Deoxyribonucleic Acid by Lymphocytes Stimulated with Phytohemagglutinin or Antigen

When human lymphocytes are cultured in the presence of phytomitogens, 70-90% of the cells undergo blast transformation and synthesize DNA. However, less than 40% of these lymphocytes actually undergo mitosis while 35-90% of the newly synthesized DNA is excreted into the media. The release of DNA by...

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Bibliographic Details
Main Authors: Rogers, John C., Boldt, David, Kornfeld, Stuart, Skinner, Sister Ann, Valeri, C. Robert
Format: Artigo
Language:Inglês
Published: 1972
Subjects:
Biological Sciences: Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC426778/
https://ncbi.nlm.nih.gov/pubmed/4505646
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