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Excretion of Deoxyribonucleic Acid by Lymphocytes Stimulated with Phytohemagglutinin or Antigen

When human lymphocytes are cultured in the presence of phytomitogens, 70-90% of the cells undergo blast transformation and synthesize DNA. However, less than 40% of these lymphocytes actually undergo mitosis while 35-90% of the newly synthesized DNA is excreted into the media. The release of DNA by...

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Rogers, John C., Boldt, David, Kornfeld, Stuart, Skinner, Sister Ann, Valeri, C. Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1972
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426778/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4505646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.7.1685
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